Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.45 |
| ▸ | FABP7 | O15540 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15874406 | 0.85 | KMT2A (0.49) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL15874638 | 0.85 | KMT2A (0.49) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL28309128 | 0.85 | KMT2A (0.49) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL12128707 | 0.83 | KMT2A (0.49) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL7809928 | 0.83 | KMT2A (0.52) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL29065249 | 0.83 | KMT2A (0.51) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL18614308 | 0.83 | FABP5 (0.49) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL5188489 | 0.83 | KMT2A (0.47) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL17079700 | 0.82 | KMT2A (0.51) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL556956 | 0.82 | KMT2A (0.51) | KMT2AFABP5FABP7CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176985-A2 | ENZYMATICALLY ACTIVATED POLYMERIC DRUG CONJUGATES | Vectramed, Inc. (US) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064486-A2 | ENZYMATICALLY ACTIVATED POLYMERIC DRUG CONJUGATES | VECTRAMED, INC. (US) | 2000-11-02 | — | — | WO | disclosed |