Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906609 | 0.84 | PNMT (0.50) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL7037299 | 0.78 | PNMT (0.52) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL3484494 | 0.78 | PNMT (0.49) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL9188893 | 0.78 | PNMT (0.49) | PNMTHTR7HTR2BNPC1RAB9A | |
| Bromide SCHEMBL15671137 | 0.76 | PNMT (0.54) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL8190225 | 0.76 | PNMT (0.50) | PNMTHTR7HTR2BNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL7518687 | 0.76 | PNMT (0.45) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL27861228 | 0.75 | PNMT (0.51) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL28463245 | 0.75 | PNMT (0.51) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL4970474 | 0.75 | PNMT (0.52) | PNMTHTR7HTR2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176985-A2 | ENZYMATICALLY ACTIVATED POLYMERIC DRUG CONJUGATES | Vectramed, Inc. (US) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064486-A2 | ENZYMATICALLY ACTIVATED POLYMERIC DRUG CONJUGATES | VECTRAMED, INC. (US) | 2000-11-02 | — | — | WO | disclosed |