SCHEMBL7518828

SCHEMBL7518828

Cc1ccccc1C(C=C(Cl)Cl)CC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSA P10619 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7524690 0.84 GLRA1 (0.40) CTSA
SCHEMBL7522384 0.81 EEF2K (0.42) CTSA
SCHEMBL4051899 0.79 CTSA (0.42) CTSA
SCHEMBL7527677 0.79 CTSA (0.41) CTSA
SCHEMBL7524496 0.78 GABBR2 (0.46) CTSA
SCHEMBL7522886 0.77 MEN1 (0.47) CTSA
SCHEMBL7527581 0.76 SMN1; SMN2 (0.42) CTSA
SCHEMBL2794839 0.76 CTSA (0.49) CTSA
SCHEMBL30781885 0.74 GABBR2 (0.48) CTSA
SCHEMBL658439 0.74 GABBR2 (0.48) CTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1181267-A1 HALOGEN COMPOUNDS Bayer Aktiengesellschaft (DE) 2002-02-27 EP disclosed
WO-2000071500-A1 HALOGEN COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2000-11-30 WO disclosed