Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524690 | 0.81 | GLRA1 (0.40) | CTSALMNA | |
| SCHEMBL7518828 | 0.79 | CTSA (0.43) | CTSA | |
| SCHEMBL7522384 | 0.76 | EEF2K (0.42) | CTSAALDH1A1ALOX15 | |
| SCHEMBL31483446 | 0.76 | CYP1A2 (0.50) | CTSAIRAK4ALDH1A1LMNAKDM4E | |
| SCHEMBL7524496 | 0.73 | GABBR2 (0.46) | CTSAKDM4EMAPT | |
| SCHEMBL7522886 | 0.71 | MEN1 (0.47) | CTSAALDH1A1LMNAGLA | |
| SCHEMBL7527581 | 0.70 | SMN1; SMN2 (0.42) | CTSAALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL9252090 | 0.68 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4ETDP1HPGD | |
| SCHEMBL25245395 | 0.67 | IRAK4 (0.53) | IRAK4ALDH1A1LMNAKDM4ETDP1 | |
| SCHEMBL7521043 | 0.66 | FFAR1 (0.44) | CTSAALDH1A1LMNAKDM4EACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181267-A1 | HALOGEN COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000071500-A1 | HALOGEN COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-30 | — | — | WO | disclosed |