SCHEMBL7519112

SCHEMBL7519112

CCNC(=O)CCCc1cccc2c1SCCO2

nearest known ligand 0.83

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 16/20 0.83
MTNR1B P49286 5/20 0.83
MPO P05164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7518813 0.91 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7517761 0.88 MTNR1A (1.00) MTNR1AMTNR1BMPO
SCHEMBL7527250 0.85 MTNR1A (0.72) MTNR1AMTNR1B
SCHEMBL7520703 0.85 MTNR1A (0.93) MTNR1AMTNR1B
SCHEMBL8476411 0.83 MTNR1A (0.73) MTNR1AMTNR1B
SCHEMBL7526974 0.81 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7523790 0.81 MTNR1A (0.86) MTNR1AMTNR1B
SCHEMBL7563666 0.81 MTNR1A (0.78) MTNR1AMTNR1B
SCHEMBL7519971 0.80 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7521096 0.79 MTNR1A (0.98) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873993-B1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2002-02-20 EP claimed
US-5919814-A Heterocyclic compounds ADIR ET COMPAGNIE (FR) 1999-07-06 US claimed
EP-0873993-A1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1998-10-28 EP claimed
EP-0873993-B1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2002-02-20 EP disclosed
US-5919814-A Heterocyclic compounds ADIR ET COMPAGNIE (FR) 1999-07-06 US disclosed
EP-0873993-A1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1998-10-28 EP disclosed