Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.93 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.71 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517761 | 0.96 | MTNR1A (1.00) | MTNR1AMTNR1BNAMPTCTNNB1WNT3A | |
| SCHEMBL7523790 | 0.91 | MTNR1A (0.86) | MTNR1AMTNR1BCTNNB1WNT3A | |
| SCHEMBL7519112 | 0.85 | MTNR1A (0.83) | MTNR1AMTNR1B | |
| SCHEMBL7518813 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8476411 | 0.81 | MTNR1A (0.73) | MTNR1AMTNR1BHDAC1HDAC6HDAC3 | |
| SCHEMBL7519971 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7524387 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BCTNNB1WNT3A | |
| SCHEMBL7521096 | 0.80 | MTNR1A (0.98) | MTNR1AMTNR1BNAMPT | |
| SCHEMBL7527250 | 0.80 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL7526974 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| CN-1197797-A | New heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-11-04 | — | — | CN | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |