SCHEMBL13778151

SCHEMBL13778151

CCSCc1cccc(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.39
BCHE P06276 2/20 0.39
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
KIF11 P52732 2/20 0.37
EPHX1 P07099 5/20 0.37
NPC1 O15118 1/20 0.37
TNF P01375 1/20 0.37
RAB9A P51151 1/20 0.37
NOD1 Q9Y239 1/20 0.37
CCR9 P51686 1/20 0.36
BACE1 P56817 1/20 0.36
TACR1 P25103 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28897758 0.90 NPC1 (0.43) ACHEBCHEHDAC4HDAC2HDAC8
SCHEMBL7519147 0.84 HTR2A (0.53) EPHX1RAB9AHTR2AHTR2CHTR2B
SCHEMBL20734675 0.82 ACHE (0.46) ACHENPC1TNFRAB9ANOD1
SCHEMBL13778149 0.81 CYP2C19 (0.49) BCHEKIF11NPC1RAB9ABACE1
SCHEMBL1653927 0.80 KIF11 (0.49) ACHEBCHEHDAC4HDAC2HDAC8
SCHEMBL30573009 0.80 KIF11 (0.49) ACHEBCHEHDAC4HDAC2HDAC8
SCHEMBL13778144 0.76 BCHE (0.45) ACHEBCHEEPHX1NPC1RAB9A
SCHEMBL13778167 0.76 CYP2C19 (0.61) ACHEEPHX1CYP1A2CYP2C19
SCHEMBL5433184 0.76 ACHE (0.46) ACHEBCHEHDAC4HDAC2HDAC8
SCHEMBL11193607 0.75 EPHX1 (0.36) KIF11EPHX1NPC1TNFRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230041563-A1 N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES OR SALTS THEREOF, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND USES THEREOF QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2023-02-09 US disclosed
US-20130041000-A1 NOVEL AZOLE COMPOUND AJINOMOTO CO., INC. (JP) 2013-02-14 US disclosed
US-20090170911-A1 NOVEL AZOLE COMPOUND AJINOMOTO CO. INC (JP) 2009-07-02 US disclosed
US-20090170911-A1 NOVEL AZOLE COMPOUND AJINOMOTO CO. INC (JP) 2009-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170911-A1 NOVEL AZOLE COMPOUND LPAR1, LPAR2, LPAR3 ACHE 3333/4885BCHE 3364/4885HDAC4 1326/4885
US-20230041563-A1 N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES OR SALTS THEREOF, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND USES THEREOF CYP2B6, CBR3, CYP2A6 ACHE 1481/4885BCHE 1002/4885HDAC4 223/4885
US-20130041000-A1 NOVEL AZOLE COMPOUND LPAR1, LPAR2, LPAR3 ACHE 3333/4885BCHE 3364/4885HDAC4 1326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.