Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302488 | 0.91 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9764152 | 0.90 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9763730 | 0.89 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14175495 | 0.86 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL17069795 | 0.85 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10883854 | 0.85 | TSHR (0.54) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14330279 | 0.83 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14444704 | 0.82 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL808948 | 0.81 | TSHR (0.58) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL18504299 | 0.81 | TSHR (0.49) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62205109-A | — | — | None | — | — | JP | disclosed |
| US-20210317297-A1 | METHODS AND COMPOSITION OF A DENTAL MODEL FOR THE MANUFACTURE OF ORTHODONTIC APPLIANCES WITHOUT THE USE OF SEPARATOR | STRUCTO PTE LTD (SG) | 2021-10-14 | — | — | US | disclosed |
| EP-3820398-A1 | METHODS AND COMPOSITION OF A DENTAL MODEL FOR THE MANUFACTURE OF ORTHODONTIC APPLIANCES WITHOUT THE USE OF SEPARATOR | Structo Pte. Ltd. (SG) | 2021-05-19 | — | — | EP | disclosed |
| US-20020016269-A1 | Particle perfume delivery system | THE PROCTER & GAMBLE CO. | 2002-02-07 | — | — | US | disclosed |
| WO-2002004586-A1 | A PARTICLE PERFUME DELIVERY SYSTEM | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-17 | — | — | WO | disclosed |
| EP-0219312-B1 | Improved fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORP (US) | 1995-12-20 | — | — | EP | disclosed |
| US-5371147-A | Silicone-containing acrylic star polymers, block copolymers and macromonomers | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5346978-A | Polymeric compositions useful in oxygen permeable contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5331067-A | Acrylic polymers containing trimethylsiloxy groups | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-07-19 | — | — | US | disclosed |
| US-5314960-A | Silicone-containing polymers, oxygen permeable hydrophilic contact lenses and methods for making these lenses and treating patients with visual impairment | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0424099-A2 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4996275-A | With silicon group-substituted addition polymers; oxygen permeability, hydrophilic, deposit resistance | POLYMER TECHNOLOGY CORPORATION (US) | 1991-02-26 | — | — | US | disclosed |
| JP-S62205109-A | OXYGEN-PERMEABLE MATERIAL | SAN CONTACT LENS:KK | 1987-09-09 | — | — | JP | disclosed |
| US-4686267-A | Fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1987-08-11 | — | — | US | disclosed |
| EP-0219312-A2 | Improved fluorine containing polymeric compositions useful in contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1987-04-22 | — | — | EP | disclosed |
| US-RE31406-E | POLYSILOXANYLALKYL ACRYLATE AND ALKYL ACRYLATE COPOLYMER | SYNTEX (U.S.A.) INC. (US) | 1983-10-04 | — | — | US | disclosed |
| EP-0075004-A1 | SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES | McCARRY, John D. (US) | 1983-03-30 | — | — | EP | disclosed |
| WO-1982003397-A1 | SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES | MCCARRY JOHN D (US) | 1982-10-14 | — | — | WO | disclosed |
| US-4182822-A | VINYL AMIDES, ESTERS OF SILANE COMPOUNDS, CONTACT LENSES | CHANG SING HSIUNG | 1980-01-08 | — | — | US | disclosed |
| US-4120570-A | POLYSILOXANYLALKYL ACRYLATE OR METHACRYLATE AND AN ALKYL ACRYLATE OR METHACRYLATE | SYNTEX (U.S.A.) INC. (US) | 1978-10-17 | — | — | US | disclosed |