SCHEMBL808948

SCHEMBL808948

C=CC(=O)OCCOCCC[Si](C)(C)O[Si](C)(C)O[Si](C)(C)CCCOCCOC(=O)C=C

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.58
ALDH1A1 P00352 4/20 0.58
TP53 P04637 3/20 0.58
HIF1A Q16665 3/20 0.58
HSD17B10 Q99714 1/20 0.58
THRB P10828 2/20 0.45
HPGD P15428 1/20 0.45
CYP3A4 P08684 2/20 0.44
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883854 0.97 TSHR (0.54) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL26740108 0.94 TSHR (0.61) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10890672 0.92 TSHR (0.59) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL17069795 0.92 TSHR (0.53) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10659632 0.91 TSHR (0.58) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL14175495 0.91 TSHR (0.55) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL9763730 0.89 TSHR (0.50) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL13561215 0.88 TSHR (0.54) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL9764152 0.88 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12131528 0.86 TSHR (0.59) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4476282-A1 COMPOSITIONS AND METHODS FOR COMPATIBILIZING POLYOLEFINS Rockytech, Ltd. (US) 2024-12-18 EP claimed
CN-118647651-A Compositions and methods for compatibilizing polyolefins 落基科技股份有限公司 2024-09-13 CN claimed
WO-2023154106-A1 COMPOSITIONS AND METHODS FOR COMPATIBILIZING POLYOLEFINS ROCKYTECH, LTD. (US) 2023-08-17 WO claimed
WO-2026099089-A1 PATTERN-CONTROLLED SURFACE RELIEF STRUCTURES COMPRISING LIQUID CRYSTALS BASF SE (DE) 2026-05-15 WO disclosed
EP-4734929-A1 SYSTEM AND METHODS FOR MODIFYING SURFACE PROPERTIES OF KERATIN-CONTAINING SURFACES Edulis Labs Inc. (US) 2026-05-06 EP disclosed
US-20260103612-A1 OVER-PRINT VARNISH FORMULATION HEWLETT PACKARD DEVELOPMENT CO (US) 2026-04-16 US disclosed
US-20260036718-A1 CONTACT LENS COMPOSITION AND CONTACT LENS PRODUCT LARGAN MEDICAL CO LTD (TW) 2026-02-05 US disclosed
EP-4686405-A1 CONTACT LENS COMPOSITION AND CONTACT LENS PRODUCT Largan Medical Co., Ltd. (TW) 2026-02-04 EP disclosed
WO-2025245116-A1 INJECTABLE AND MOLDABLE ELASTOMERS AND MEDICAL DEVICES VATANKHAH VARNOSFADERANI MOHAMMAD (US) 2025-11-27 WO disclosed
US-12460096-B2 Over-print varnish formulation HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2025-11-04 US disclosed
US-12442956-B2 Contact lens product LARGAN MEDICAL CO., LTD. (TW) 2025-10-14 US disclosed
US-11319454-B2 Polyurethane-based binder dispersion HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-05-03 US disclosed
WO-2022051762-A2 NON-LEACHING WATERBORNE VIRUCIDAL/BACTERICIDAL COATING CURRAN BIOTECH INC. (US) 2022-03-10 WO disclosed
US-8492513-B2 Method for enhancing water content of silicone hydrogel contact lens FAR EASTERN NEW CENTURY CORPORATION (TW) 2013-07-23 US disclosed
US-20120214898-A1 SILICONE HYDROGEL WITH HIGH WATER CONTENT FAR EASTERN NEW CENTURY CORPORATION (TW) 2012-08-23 US disclosed
US-20120214899-A1 METHOD FOR ENHANCING WATER CONTENT OF SILICONE HYDROGEL CONTACT LENS FAR EASTERN NEW CENTURY CORPORATION (TW) 2012-08-23 US disclosed
US-20120115979-A1 CHLORINATED POLYMER ENHANCING WETTABILITY OF SILICONE HYDROGEL, SILICONE HYDROGEL COMPRISING THE SAME AND OCULAR ARTICLE MADE THEREFROM FAR EASTERN NEW CENTURY CORPORATION (TW) 2012-05-10 US disclosed
US-7906563-B2 Polysiloxane-based prepolymer and hydrogel FAR EASTERN NEW CENTURY CORPORATION (TW) 2011-03-15 US disclosed
US-20090170976-A1 Polysiloxane-based prepolymer and hydrogel FAR EASTERN TEXTILE LTD. 2009-07-02 US disclosed
US-4743667-A ACRYLATED SILOXXANES, OXYGEN PERMEABLE NIPPON CONTACT LENS, INC. (JP) 1988-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103612-A1 OVER-PRINT VARNISH FORMULATION PUF60, U2SURP, VMP1 TSHR 2815/4885ALDH1A1 2853/4885TP53 1543/4885
US-20260036718-A1 CONTACT LENS COMPOSITION AND CONTACT LENS PRODUCT CRYAB, CRYZ, RPL5 TSHR 3452/4885ALDH1A1 3369/4885TP53 1698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.