Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983836 | 0.74 | TSHR (0.39) | ACHETSHRMAPT | |
| SCHEMBL11528203 | 0.72 | ACHE (0.38) | ACHETSHRMAPT | |
| SCHEMBL1054532 | 0.71 | ACHE (0.41) | ACHETSHR | |
| SCHEMBL103282 | 0.68 | NR1H2 (0.37) | ACHETSHR | |
| SCHEMBL1314449 | 0.66 | TSHR (0.45) | ACHETSHR | |
| SCHEMBL3162440 | 0.66 | TSHR (0.45) | ACHETSHR | |
| SCHEMBL1302209 | 0.66 | TSHR (0.45) | ACHETSHR | |
| SCHEMBL2098655 | 0.66 | TSHR (0.45) | ACHETSHR | |
| SCHEMBL8161345 | 0.65 | TSHR (0.50) | ACHETSHRMAPT | |
| SCHEMBL1054610 | 0.65 | TSHR (0.50) | ACHETSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-B1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5608095-A | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-04 | — | — | US | disclosed |