Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519467 | 1.00 | HRH1 (0.45) | HRH1MAOAMAOBSMN1; SMN2MAPT | |
| SCHEMBL825190 | 0.83 | SMN1; SMN2 (0.47) | MAOAMAOBSMN1; SMN2MAPTLIN28A | |
| SCHEMBL825188 | 0.83 | SMN1; SMN2 (0.47) | MAOAMAOBSMN1; SMN2MAPTLIN28A | |
| SCHEMBL6866606 | 0.79 | MAOA (0.57) | HRH1MAOAMAOBSMN1; SMN2CHRM2 | |
| SCHEMBL6866612 | 0.79 | MAOA (0.57) | HRH1MAOAMAOBSMN1; SMN2CHRM2 | |
| SCHEMBL7523864 | 0.73 | TDP1 (0.47) | HRH1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL7523860 | 0.73 | TDP1 (0.47) | HRH1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL13373201 | 0.73 | MAOA (0.50) | MAOAMAOBSMN1; SMN2MAPTCHRM2 | |
| SCHEMBL11699253 | 0.71 | SMN1; SMN2 (0.51) | HRH1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL6375937 | 0.70 | CHRM2 (0.57) | HRH1MAOAMAOBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020066542-A1 | Transition metal complexes with polydentate ligands for enhancing the bleaching and delignifying effect of peroxo compounds | DEGUSSA AG (DE) | 2002-06-06 | — | — | US | disclosed |
| EP-1199402-A2 | Process for delignifying and/or bleaching fibrous material | Degussa AG (DE) | 2002-04-24 | — | — | EP | disclosed |