SCHEMBL7519660

SCHEMBL7519660

CC(=O)OC(O)C(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 10/20 0.75
▸ LMNA P02545 2/20 0.75
▸ PGR P06401 3/20 0.71
▸ SERPINA6 P08185 2/20 0.71
▸ AR P10275 2/20 0.71
▸ CHRM1 P11229 2/20 0.71
▸ NR3C1 P04150 6/20 0.68
▸ SMN1; SMN2 Q16637 3/20 0.68
▸ CYP2C19 P33261 2/20 0.68
▸ HSD17B10 Q99714 2/20 0.68
▸ CYP3A4 P08684 2/20 0.68
▸ NFKB1 P19838 2/20 0.68
▸ MAPT P10636 2/20 0.68
▸ NR3C2 P08235 2/20 0.68
▸ SHBG P04278 1/20 0.68
▸ KMT2A Q03164 1/20 0.68
▸ PMP22 Q01453 1/20 0.59
▸ TSHR P16473 1/20 0.59
▸ POLB P06746 1/20 0.59
▸ GAA P10253 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11814284 0.90 HIF1A (0.81) HIF1ALMNAPGRSERPINA6AR
SCHEMBL8920369 0.90 HIF1A (0.67) HIF1ALMNAPGRSERPINA6AR
SCHEMBL16020569 0.88 HIF1A (0.78) HIF1ALMNAPGRSERPINA6AR
SCHEMBL332585 0.88 HIF1A (0.69) HIF1ALMNAPGRSERPINA6AR
SCHEMBL10733115 0.88 HIF1A (0.69) HIF1ALMNAPGRSERPINA6AR
SCHEMBL8071547 0.87 HIF1A (0.77) HIF1ALMNAPGRSERPINA6AR
SCHEMBL7614974 0.87 HIF1A (0.77) HIF1ALMNAPGRSERPINA6AR
SCHEMBL11118863 0.87 HIF1A (0.74) HIF1ALMNAPGRSERPINA6AR
SCHEMBL9437393 0.86 HIF1A (0.75) HIF1ALMNAPGRSERPINA6AR
SCHEMBL9802150 0.86 HIF1A (0.75) HIF1ALMNAPGRSERPINA6AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733903-B1 Immunoassay for the detection of urinary cortisol and reagents therefor IMMUNOTECH SA (FR) 2002-02-27 — — EP disclosed
US-5910575-A MONOCLONAL ANTIBODY WHICH BINDS TO (125)I-LABELED DERIVATIVES OF CORTISOL-3-CARBOXYMETHYLOXIME-HISTAMINE AND PREFERENTIALLY BINDS TO UNLABELED SYN ISOMER OVER UNLABELED ANTI ISOMER; FOR COMPETITIVE RADIOIMMUNOASSAY IMMUNOTECH (FR) 1999-06-08 — — US disclosed
EP-0733903-A1 Immunoassay for the detection of urinary cortisol and reagents therefor Société Anonyme dite: IMMUNOTECH S.A. (FR) 1996-09-25 — — EP disclosed
US-5022972-A Applying controlled voltage to suspension, determining velocity as function of applied potential MTA Kutatasi Eszkozoket Kivitelezo Vallata (HU) 1991-06-11 — — US disclosed
EP-0287625-A1 PROCESS FOR MEASURING AND DETERMINING ZETA-POTENTIAL IN A LAMINARLY FLOWING MEDIUM FOR PRACTICAL PURPOSES MTA KUTATASI ESZKÖZÖKET KIVITELEZÖ VALLALAT (HU) 1988-10-26 — — EP disclosed
WO-1988003265-A1 PROCESS FOR MEASURING AND DETERMINING ZETA-POTENTIAL IN A LAMINARLY FLOWING MEDIUM FOR PRACTICAL PURPOSES MTA KUTATÁSI ESZKÖZÖKET KIVITELEZO^" VÁLLALAT (HU) 1988-05-05 — — WO disclosed
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