Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548184 | 0.77 | ESR1 (0.44) | LMNAHSD17B10KDM1AMAPTHSD17B1 | |
| SCHEMBL7548147 | 0.76 | PPARD (0.37) | LMNAHSD17B10MAPTHSD17B1RECQL | |
| SCHEMBL7547080 | 0.76 | PPARD (0.37) | LMNAHSD17B10MAPTHSD17B1RECQL | |
| SCHEMBL21137452 | 0.73 | LMNA (0.39) | LMNAHSD17B10KDM1AMAPTHSD17B1 | |
| SCHEMBL7519471 | 0.71 | CYP19A1 (0.39) | LMNAHSD17B10KDM1AMAPTHSD17B1 | |
| SCHEMBL7515992 | 0.71 | PPARD (0.38) | LMNAHSD17B10MAPTHSD17B1RECQL | |
| SCHEMBL8048890 | 0.69 | LMNA (0.56) | LMNAHSD17B10KDM1AMAPTHSD17B1 | |
| SCHEMBL8048425 | 0.69 | LMNA (0.56) | LMNAHSD17B10KDM1AMAPTHSD17B1 | |
| SCHEMBL11671496 | 0.67 | STS (0.60) | LMNAHSD17B10MAPTHSD17B1RECQL | |
| SCHEMBL11222251 | 0.67 | STS (0.60) | LMNAHSD17B10MAPTHSD17B1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165596-A1 | 14,15-.ALPHA.-METHYLENE EQUILENINE DERIVATIVES, METHODS FOR PRODUCING THE SAME AND MEDICAMENTS CONTAINING THEM | Jenapharm GmbH & Co. KG (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059922-A1 | 14,15-.ALPHA.-METHYLENE EQUILENINE DERIVATIVES, METHODS FOR PRODUCING THE SAME AND MEDICAMENTS CONTAINING THEM | JENAPHARM GMBH & CO. KG (DE) | 2000-10-12 | — | — | WO | disclosed |