SCHEMBL7520041

SCHEMBL7520041

N#CCCCc1cccc2c1OC=CO2

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 5/20 0.48
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MPO P05164 1/20 0.33
SLC6A4 P31645 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7522094 0.78 MTNR1A (0.51) MTNR1AMPOSLC6A4
SCHEMBL7521660 0.78 MTNR1A (0.55) MTNR1A
SCHEMBL7519080 0.76 MTNR1A (0.53) MTNR1ASLC6A4
SCHEMBL8479546 0.74 MTNR1A (0.61) MTNR1AMEN1KMT2A
SCHEMBL7519831 0.70 MTNR1A (0.67) MTNR1AMPO
SCHEMBL7519095 0.70 MTNR1A (0.46) MTNR1A
SCHEMBL7523017 0.69 MTNR1A (0.73) MTNR1A
SCHEMBL28778330 0.68 MTNR1A (0.44) MTNR1A
SCHEMBL1150773 0.68 TAAR1 (0.50) SLC6A4ATML3MBTL1
SCHEMBL27658164 0.67 DPP4 (0.48) KMT2AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873993-B1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2002-02-20 EP disclosed
US-5919814-A Heterocyclic compounds ADIR ET COMPAGNIE (FR) 1999-07-06 US disclosed
EP-0873993-A1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1998-10-28 EP disclosed