Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522094 | 0.82 | MTNR1A (0.51) | MTNR1A | |
| SCHEMBL8479546 | 0.81 | MTNR1A (0.61) | MTNR1A | |
| SCHEMBL7519095 | 0.81 | MTNR1A (0.46) | MTNR1A | |
| SCHEMBL28778330 | 0.79 | MTNR1A (0.44) | MTNR1A | |
| SCHEMBL7520041 | 0.78 | MTNR1A (0.48) | MTNR1A | |
| SCHEMBL7519831 | 0.77 | MTNR1A (0.67) | MTNR1A | |
| SCHEMBL7523017 | 0.76 | MTNR1A (0.73) | MTNR1A | |
| SCHEMBL7526419 | 0.74 | MTNR1A (0.61) | MTNR1A | |
| SCHEMBL8024702 | 0.73 | MTNR1A (0.38) | MTNR1A | |
| SCHEMBL7518316 | 0.73 | MTNR1A (0.84) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |