Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NSD2 | O96028 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28199759 | 0.93 | MAPT (0.46) | MAPTALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL215956 | 0.76 | MAPT (0.43) | MAPTALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL28058582 | 0.74 | DDB1 (0.36) | GAAMEN1KMT2ARAB9APABPC1 | |
| SCHEMBL5576934 | 0.74 | MAPT (0.59) | MAPTALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL2047398 | 0.72 | CD44 (0.44) | ALDH1A1L3MBTL1MAPK1TDP1PDK2 | |
| SCHEMBL1768344 | 0.72 | MAPT (0.52) | MAPTALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL3786323 | 0.72 | ALDH1A1 (0.52) | MAPTALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL27408876 | 0.71 | CD44 (0.43) | ALDH1A1L3MBTL1MAPK1TDP1PDK2 | |
| SCHEMBL2919461 | 0.70 | MAPT (0.52) | MAPTALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL6760678 | 0.70 | ADORA2A (0.48) | MAPTALDH1A1L3MBTL1TDP1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773238-B1 | Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems | FINA TECHNOLOGY (US) | 2002-03-20 | — | — | EP | claimed |
| EP-0773239-B1 | Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems | FINA TECHNOLOGY (US) | 2001-12-05 | — | — | EP | claimed |