⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29111459 | 0.78 | — | — | |
| SCHEMBL3949388 | 0.74 | — | — | |
| SCHEMBL25263047 | 0.72 | — | — | |
| SCHEMBL4353030 | 0.72 | POLA1 (0.35) | — | |
| SCHEMBL17965483 | 0.68 | — | — | |
| SCHEMBL5347884 | 0.68 | MEN1 (0.33) | — | |
| SCHEMBL28231867 | 0.68 | MAPK1 (0.32) | — | |
| SCHEMBL28517989 | 0.67 | AKR1B1 (0.31) | — | |
| SCHEMBL6106227 | 0.66 | NPSR1 (0.31) | — | |
| SCHEMBL11111902 | 0.65 | CA2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1353689-A | Novel hydroxamic acid derivatives | DAIICHI PREC KAGAKU (JP) | 2002-06-12 | — | — | CN | disclosed |
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| CN-1284060-A | Novel metalloprotease inhibitors | FUJI YAKUHIN KOGYO KK (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |