Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520175 | 0.84 | ESR1 (0.35) | ESR1ESR2KDM4EALDH1A1MAPT | |
| SCHEMBL28499947 | 0.74 | ABL1 (0.32) | ESR1ESR2MAPTPTGS2 | |
| SCHEMBL7517561 | 0.69 | LCK (0.42) | KDM4EALDH1A1MAPTHPGDCYP19A1 | |
| SCHEMBL7517571 | 0.69 | LCK (0.42) | KDM4EALDH1A1MAPTHPGDCYP19A1 | |
| SCHEMBL9458260 | 0.66 | MAPT (0.42) | MAPT | |
| SCHEMBL1882235 | 0.66 | ALDH1A1 (0.50) | ALDH1A1MAPT | |
| SCHEMBL8886564 | 0.66 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDPTGS2 | |
| SCHEMBL28499949 | 0.65 | NQO2 (0.31) | ESR1ESR2MAPTPTGS2 | |
| SCHEMBL9320133 | 0.64 | MAPT (0.48) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6231834 | 0.62 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506314-B1 | Process for preparing vinylically-unsaturated compounds | DOW CHEMICAL CO (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5264646-A | Vinylation, benzocyclobutenes, polysiloxanes | THE DOW CHEMICAL COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| US-5243068-A | Alkenylation with organic halides | THE DOW CHEMICAL COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0506314-A2 | Process for preparing vinylically-unsaturated compounds | THE DOW CHEMICAL COMPANY (US) | 1992-09-30 | — | — | EP | disclosed |
| US-5136069-A | Reacting with halogenated organic compound in presence of palladium complex catalyst and inorganic hydrogen halide acceptor | THE DOW CHEMICAL COMPANY (US) | 1992-08-04 | — | — | US | disclosed |