Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123084 | 0.80 | TSHR (0.52) | MAPTL3MBTL1ALDH1A1SMN1; SMN2CA5A | |
| SCHEMBL1974334 | 0.78 | LMNA (0.33) | MAPTLMNAL3MBTL1 | |
| SCHEMBL6231834 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9365820 | 0.78 | TSHR (0.50) | MAPTL3MBTL1ALDH1A1SMN1; SMN2CA5A | |
| SCHEMBL9295482 | 0.78 | PTPRC (0.62) | MAPTHPGDKMT2ALMNAALDH1A1 | |
| SCHEMBL28499949 | 0.76 | NQO2 (0.31) | MAPTKMT2ALMNA | |
| SCHEMBL28440733 | 0.76 | MAPT (0.55) | MAPTRAB9ANPC1CYP2A6PKM | |
| SCHEMBL9542326 | 0.75 | ATM (0.58) | RAB9ANPC1KMT2ALMNAL3MBTL1 | |
| SCHEMBL50646 | 0.74 | MAPT (0.68) | MAPTRAB9ANPC1HPGDKMT2A | |
| SCHEMBL834744 | 0.74 | CYP2A6 (0.68) | MAPTRAB9ANPC1CYP2A6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5349095-A | Process for preparing hydroxyalkylbenzocyclobutenes | THE DOW CHEMICAL COMPANY (US) | 1994-09-20 | — | — | US | disclosed |