SCHEMBL7520199

SCHEMBL7520199

CCCC(=O)NCCCc1cccc2c1OC=CO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 13/20 1.00
MTNR1B P49286 11/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7518316 0.91 MTNR1A (0.84) MTNR1AMTNR1B
SCHEMBL7523017 0.84 MTNR1A (0.73) MTNR1AMTNR1B
SCHEMBL7520573 0.81 MTNR1A (0.73) MTNR1AMTNR1B
SCHEMBL7519831 0.80 MTNR1A (0.67) MTNR1AMTNR1B
SCHEMBL8479546 0.77 MTNR1A (0.61) MTNR1A
SCHEMBL7526968 0.74 MTNR1A (0.73) MTNR1AMTNR1B
SCHEMBL7521660 0.72 MTNR1A (0.55) MTNR1A
SCHEMBL8928193 0.71 MTNR1A (0.55) MTNR1AMTNR1B
SCHEMBL6781677 0.70 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL6786474 0.69 MTNR1A (1.00) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873993-B1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2002-02-20 EP claimed
EP-0873993-A1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1998-10-28 EP claimed
EP-0873993-B1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2002-02-20 EP disclosed
US-5919814-A Heterocyclic compounds ADIR ET COMPAGNIE (FR) 1999-07-06 US disclosed
EP-0873993-A1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1998-10-28 EP disclosed