Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.80 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.72 |
| ▸ | MMP3 | P08254 | 5/20 | 0.70 |
| ▸ | MMP1 | P03956 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128810 | 1.00 | MMP2 (0.80) | MMP2HDAC1HDAC2MMP3MMP1 | |
| SCHEMBL13862226 | 1.00 | MMP2 (0.80) | MMP2HDAC1HDAC2MMP3MMP1 | |
| SCHEMBL8657014 | 1.00 | MMP2 (0.80) | MMP2HDAC1HDAC2MMP3MMP1 | |
| SCHEMBL5097470 | 1.00 | MMP2 (0.80) | MMP2HDAC1HDAC2MMP3MMP1 | |
| SCHEMBL6252232 | 1.00 | MMP2 (0.80) | MMP2HDAC1HDAC2MMP3MMP1 | |
| SCHEMBL4273348 | 0.98 | MMP2 (0.82) | MMP2HDAC1HDAC2MMP3MMP1 | |
| SCHEMBL3952240 | 0.95 | MMP2 (0.71) | MMP2HDAC1HDAC2MMP3MMP1 | |
| SCHEMBL5516422 | 0.95 | MMP2 (0.71) | MMP2HDAC1HDAC2MMP3MMP1 | |
| SCHEMBL1139009 | 0.95 | MMP2 (0.71) | MMP2HDAC1HDAC2MMP3MMP1 | |
| SCHEMBL1285747 | 0.94 | MMP2 (0.85) | MMP2HDAC1HDAC2MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339114-B1 | APPLYING LIQUID CRYSTALLINE COMPOUND TO A TOOTH IN A PATIENT'S MOUTH, AND POLYMERIZING TO FORM POLYMERIC DENTAL PRODUCT | DENTSPLY DETREY GMBH (DE) | 2002-01-15 | — | — | US | disclosed |
| EP-0861230-B1 | LIQUID CRYSTALLINE (METH)ACRYLATE COMPOUNDS, COMPOSITION AND METHOD | DENTSPLY INT INC (US) | 2002-01-02 | — | — | EP | disclosed |
| US-5998499-A | DENTAL ADHESIVE; SHRINKAGE INHIBITION | DENTSPLY G.M.B.H. (DE) | 1999-12-07 | — | — | US | disclosed |