Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.82 |
| ▸ | MMP3 | P08254 | 5/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.70 |
| ▸ | MMP1 | P03956 | 1/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.62 |
| ▸ | MMP13 | P45452 | 1/20 | 0.62 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862226 | 0.98 | MMP2 (0.80) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL8657014 | 0.98 | MMP2 (0.80) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL5097470 | 0.98 | MMP2 (0.80) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL7520274 | 0.98 | MMP2 (0.80) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL6252232 | 0.98 | MMP2 (0.80) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL9128810 | 0.98 | MMP2 (0.80) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL1285747 | 0.95 | MMP2 (0.85) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL4614541 | 0.95 | MMP2 (0.73) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL3952240 | 0.94 | MMP2 (0.71) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL5516422 | 0.94 | MMP2 (0.71) | MMP2MMP3HDAC1HDAC2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585983-B2 | Alkylenedioxythiophenes and poly(alkylenedioxythiophenes) containing mesogenic groups | H.C. STARCK, GMBH (DE) | 2009-09-08 | — | — | US | disclosed |
| US-7585983-B2 | Alkylenedioxythiophenes and poly(alkylenedioxythiophenes) containing mesogenic groups | H.C. STARCK, GMBH (DE) | 2009-09-08 | — | — | US | disclosed |
| US-20040227128-A1 | Alkylenedioxythiophenes and poly(alkylenedioxythiophenes) containing mesogenic groups | H.C. STARCK GMBH (DE) | 2004-11-18 | — | — | US | disclosed |
| EP-1440974-A2 | Alkylenedioxythiophenes and Poly(alkylendioxythiophenes) with mesogenic groups | Bayer Chemicals AG (DE) | 2004-07-28 | — | — | EP | disclosed |
| EP-0874808-B1 | BIPHENYL HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LAB (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-0874808-A1 | BIPHENYL HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | Abbott Laboratories (US) | 1998-11-04 | — | — | EP | disclosed |
| US-5665777-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1997-09-09 | — | — | US | disclosed |
| WO-1997018188-A1 | BIPHENYL HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 1997-05-22 | — | — | WO | disclosed |