Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | CDC25A | P30304 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | PGR | P06401 | 1/20 | 0.68 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.68 |
| ▸ | VDR | P11473 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518602 | 0.89 | MEN1 (0.68) | MEN1KMT2AMAPTCDC25AALDH1A1 | |
| SCHEMBL7515258 | 0.88 | MEN1 (0.69) | MEN1KMT2AMAPTCDC25AALDH1A1 | |
| SCHEMBL7516578 | 0.85 | MEN1 (0.81) | MEN1KMT2AMAPTCDC25AALDH1A1 | |
| SCHEMBL11129087 | 0.85 | MEN1 (0.81) | MEN1KMT2AMAPTCDC25AALDH1A1 | |
| SCHEMBL7522031 | 0.83 | ADORA3 (0.71) | MEN1KMT2AMAPTCDC25AALDH1A1 | |
| SCHEMBL3186509 | 0.83 | MEN1 (0.69) | MEN1KMT2AMAPTCDC25AALDH1A1 | |
| SCHEMBL1890289 | 0.81 | MEN1 (0.71) | MEN1KMT2AMAPTCDC25AALDH1A1 | |
| SCHEMBL7513927 | 0.81 | MEN1 (0.69) | MEN1KMT2AMAPTCDC25AALDH1A1 | |
| Cholecalciferol SCHEMBL23878716 | 0.81 | MEN1 (1.00) | MEN1KMT2AMAPTCDC25AALDH1A1 | |
| Cholecalciferol SCHEMBL13989117 | 0.81 | MEN1 (1.00) | MEN1KMT2AMAPTCDC25AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1172442-A1 | VITAMIN D DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | MERCIAN CORPORATION (JP) | 2002-01-16 | — | — | EP | disclosed |