Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.71 |
| ▸ | VDR | P11473 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | CDC25A | P30304 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | PGR | P06401 | 1/20 | 0.71 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.71 |
| ▸ | DRD3 | P35462 | 1/20 | 0.71 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10847899 | 0.91 | VDR (0.61) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL11129087 | 0.88 | MEN1 (0.81) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL7516578 | 0.88 | MEN1 (0.81) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL22577759 | 0.87 | MAPT (0.77) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL7211135 | 0.87 | MAPT (0.77) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL378182 | 0.87 | MAPT (0.77) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL28255174 | 0.87 | MAPT (0.77) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL4974563 | 0.87 | MEN1 (0.68) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL4281108 | 0.86 | VDR (0.70) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL11681021 | 0.85 | ADORA3 (0.76) | MEN1KMT2AMAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588539-B1 | Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3 | TEVA PHARMA (IL) | 1997-02-05 | — | — | EP | claimed |
| US-4617297-A | CALCIUM METABOLIC DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1986-10-14 | — | — | US | claimed |
| US-20210148933-A1 | METHODS AND ASSAYS FOR USE IN DIAGNOSIS OF LAMINITIS | Pepsis Limited (GB) | 2021-05-20 | — | — | US | disclosed |
| US-20140200201-A1 | Enzymatic Production or Chemical Synthesis and Uses for 5,7-Dienes and UVB Conversion Products Thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2014-07-17 | — | — | US | disclosed |
| US-20120258938-A1 | Enzymatic Production or Chemical Synthesis and Uses for 5,7-Dienes and UVB Conversion Products Thereof | SLOMINSKI ANDREJ (US) | 2012-10-11 | — | — | US | disclosed |
| EP-2352500-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | Celtaxsys, INC. (US) | 2011-08-10 | — | — | EP | disclosed |
| US-20110118228-A1 | Enzymatic production or chemical synthesis and uses for 5,7-dienes and UVB conversion products thereof | SLOMINSKI ANDRZEJ | 2011-05-19 | — | — | US | disclosed |
| WO-2010042788-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | CELTAXSYS, INC. (US) | 2010-04-15 | — | — | WO | disclosed |
| WO-2009108388-A2 | ENZYMATIC PRODUCTION OR CHEMICAL SYNTHESIS AND USES FOR 5,7-DIENES AND UVB CONVERSION PRODUCTS THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2009-09-03 | — | — | WO | disclosed |
| US-5120722-A | Trihydroxy-cholecacliferol and trihydroxy-ergocalciferol for treating leukemia | HOFFMANN-LA ROCHE INC. (US) | 1992-06-09 | — | — | US | disclosed |
| US-5110958-A | Antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1992-05-05 | — | — | US | disclosed |
| US-4749710-A | HYDROXYLATED ERGOCALCIFEROLS; ADMINISTERING | HOFFMANN-LA ROCHE INC. (US) | 1988-06-07 | — | — | US | disclosed |
| US-4617297-A | CALCIUM METABOLIC DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1986-10-14 | — | — | US | disclosed |
| US-4617297-A | CALCIUM METABOLIC DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1986-10-14 | — | — | US | disclosed |
| US-4223131-A | VITAMIN D-LIKE, INCREASES SERUM CALCIUM | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-09-16 | — | — | US | disclosed |
| WO-1980001565-A1 | 25-HYDROXYCHOLECALCIFEROL-26,23-LACTONE | WISCONSIN ALUMNI RES FOUND (US) | 1980-08-07 | — | — | WO | disclosed |