Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.44 |
| ▸ | GHSR | Q92847 | 5/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336766 | 0.85 | OPRD1 (0.53) | ABCB1PARP1FKBP1AHTTOPRD1 | |
| SCHEMBL4738328 | 0.85 | OPRD1 (0.53) | ABCB1PARP1FKBP1AHTTOPRD1 | |
| SCHEMBL337363 | 0.85 | OPRD1 (0.53) | ABCB1PARP1FKBP1AHTTOPRD1 | |
| SCHEMBL20528094 | 0.84 | KDM1A (0.53) | ABCB1PARP1FKBP1AOPRD1CTSL | |
| SCHEMBL20522962 | 0.84 | KDM1A (0.53) | ABCB1PARP1FKBP1AOPRD1CTSL | |
| SCHEMBL30511036 | 0.84 | KDM1A (0.53) | ABCB1PARP1FKBP1AOPRD1CTSL | |
| SCHEMBL19056526 | 0.83 | ABCB1 (0.49) | ABCB1PARP1SYKHTTMAPT | |
| SCHEMBL27760935 | 0.82 | ABCB1 (0.52) | ABCB1PARP1FKBP1ASYKHTT | |
| SCHEMBL18989117 | 0.82 | ABCB1 (0.48) | ABCB1PARP1FKBP1ASYKHTT | |
| SCHEMBL15880038 | 0.81 | NR1H2 (0.53) | ABCB1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPN1, PTPRO, PTPRS | ABCB1 1327/4885PARP1 4188/4885FKBP1A 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.