Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1900487 | 0.83 | CYP19A1 (0.70) | CYP19A1SMN1; SMN2NR1I2ALDH1A1ESR1 | |
| SCHEMBL1900489 | 0.83 | CYP19A1 (0.70) | CYP19A1SMN1; SMN2NR1I2ALDH1A1ESR1 | |
| SCHEMBL3639319 | 0.82 | CYP19A1 (0.63) | CYP19A1SMN1; SMN2NR1I2ALDH1A1ESR1 | |
| SCHEMBL42713 | 0.78 | CYP19A1 (1.00) | CYP19A1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL2600419 | 0.78 | CYP19A1 (1.00) | CYP19A1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL42712 | 0.78 | CYP19A1 (1.00) | CYP19A1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL6821320 | 0.77 | CYP19A1 (0.78) | CYP19A1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL7097095 | 0.77 | CYP19A1 (0.78) | CYP19A1SMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL11425175 | 0.76 | CYP19A1 (0.64) | CYP19A1NR1I2NR3C1PGRCYP3A4 | |
| SCHEMBL7882955 | 0.76 | CYP19A1 (0.64) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103391-A1 | Novel androstanes for inducing hypothalamic effects | BERLINER DAVID L (US) | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103391-A1 | Novel androstanes for inducing hypothalamic effects | FABP7, NR3C2, NR3C1 | CYP19A1 109/4885SMN1; SMN2 4660/4885NR1I2 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.