Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 5/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519215 | 0.90 | AKR1B1 (0.42) | CTSAAKR1B1GAAKMT2A | |
| SCHEMBL7528570 | 0.89 | KDM4E (0.40) | KDM4ECTSAITGB2ICAM1ITGAL | |
| SCHEMBL7521830 | 0.87 | ITGB2 (0.40) | KDM4ECTSAITGB2ICAM1ITGAL | |
| SCHEMBL7522384 | 0.78 | EEF2K (0.42) | CTSAGAAKMT2A | |
| SCHEMBL7522886 | 0.77 | MEN1 (0.47) | CTSAAKR1B1KMT2A | |
| SCHEMBL28542557 | 0.76 | KDM4E (0.44) | KDM4ECTSAITGB2ICAM1ITGAL | |
| SCHEMBL20535553 | 0.76 | KDM4E (0.44) | KDM4ECTSAITGB2ICAM1ITGAL | |
| SCHEMBL21631976 | 0.74 | GABBR2 (0.50) | KDM4EITGB2ICAM1ITGALKMT2A | |
| SCHEMBL21631984 | 0.72 | KDM4E (0.44) | KDM4ECTSAITGB2ICAM1ITGAL | |
| SCHEMBL7520247 | 0.72 | ALDH1A1 (0.39) | CTSAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181267-A1 | HALOGEN COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000071500-A1 | HALOGEN COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-30 | — | — | WO | disclosed |