SCHEMBL7520802

SCHEMBL7520802

[N-]=[N+]=CCC(=O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
MAPK1 P28482 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
HCAR2 Q8TDS4 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 4/20 0.45
CDC25B P30305 1/20 0.43
CA12 O43570 1/20 0.42
AKR1B10 O60218 1/20 0.42
AKR1B1 P15121 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568209 0.80 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL6650547 0.80 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL6711344 0.80 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL2562532 0.79 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL347596 0.77 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL7651972 0.77 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL7718190 0.77 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL10826970 0.76 ALDH1A1 (0.45) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL9677845 0.76 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL29901844 0.76 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1HCAR2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1169328-A2 AVERMECTIN DERIVATIVES Bayer Aktiengesellschaft (DE) 2002-01-09 EP disclosed
WO-2000058328-A2 AVERMECTIN DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2000-10-05 WO disclosed
US-4609495-A BETA-LACTAMASE INHIBITORS, ANTIBIOTICS BEECHAM GROUP P.L.C. (GB) 1986-09-02 US disclosed
US-4548815-A SYNERGISTIC MIXTURE OF AN OXAPENICILLIN AND A PENICILLIN BEECHAM GROUP P.L.C. (GB) 1985-10-22 US disclosed
US-4228174-A ANTIBIOTICS BEECHAM GROUP LIMITED (GB) 1980-10-14 US disclosed