SCHEMBL7521065

SCHEMBL7521065

C=Cc1ccc2c(c1)Nc1ccccc1O2

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 10/20 0.60
HTR2B P41595 2/20 0.43
HTR7 P34969 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
GAA P10253 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
DHODH Q02127 1/20 0.36
MAPT P10636 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28230706 0.83 ALOX5 (0.64) ALOX5HTR2BHTR7MEN1KMT2A
SCHEMBL8204765 0.80 ALOX5 (0.41) ALOX5HTR2BTDP1ALDH1A1
SCHEMBL10512849 0.77 AHR (0.48) ALOX5TDP1ALDH1A1NPC1RAB9A
Phenoxazine SCHEMBL7862 0.77 ALOX5 (1.00) ALOX5HTR2BHTR7MEN1KMT2A
Phenoxazine SCHEMBL29355714 0.77 ALOX5 (1.00) ALOX5HTR2BHTR7MEN1KMT2A
Phenoxazine SCHEMBL28844098 0.77 ALOX5 (1.00) ALOX5HTR2BHTR7MEN1KMT2A
Phenoxazine SCHEMBL6310178 0.77 ALOX5 (1.00) ALOX5HTR2BHTR7MEN1KMT2A
Phenoxazine SCHEMBL25275195 0.74 ALOX5 (0.94) ALOX5HTR2BHTR7MEN1KMT2A
Phenoxazine SCHEMBL5808288 0.74 ALOX5 (0.94) ALOX5HTR2BHTR7MEN1KMT2A
Phenoxazine SCHEMBL20840431 0.74 ALOX5 (0.94) ALOX5HTR2BHTR7MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6489080-B2 CONTAINING ACID GENERATOR FUJI PHOTO FILM CO., LTD. (JP) 2002-12-03 US disclosed
US-20020015916-A1 POSITIVE RESIST COMPOSITION FUJI PHOTO FILM CO., LTD. (JP) 2002-02-07 US disclosed