Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255889 | 0.80 | HPGD (0.54) | MAOBHPGDALOX15SMN1; SMN2NPC1 | |
| SCHEMBL7256712 | 0.77 | GAA (0.56) | MAOBHPGDALOX15SMN1; SMN2NPC1 | |
| SCHEMBL692795 | 0.76 | ALDH1A1 (0.50) | HPGDSMN1; SMN2NPC1CYP1A2CYP2D6 | |
| SCHEMBL11660642 | 0.75 | HPGD (0.53) | MAOBHPGDALOX15SMN1; SMN2NPC1 | |
| SCHEMBL2531725 | 0.74 | HPGD (0.45) | MAOBHPGDALOX15SMN1; SMN2NPC1 | |
| SCHEMBL11798134 | 0.73 | NPC1 (0.58) | MAOBHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL799896 | 0.72 | SMN1; SMN2 (0.70) | MAOBHPGDALOX15SMN1; SMN2NPC1 | |
| SCHEMBL11797464 | 0.71 | KMT2A (0.59) | HPGDSMN1; SMN2NPC1CYP1A2CYP2D6 | |
| SCHEMBL28138503 | 0.71 | ALDH1A1 (0.52) | MAOBSMN1; SMN2HDAC1HDAC2GAA | |
| SCHEMBL8652685 | 0.71 | CA12 (0.56) | MAOBHPGDALOX15SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175198-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2002-01-30 | — | — | EP | disclosed |
| WO-2001062220-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2001-08-30 | — | — | WO | disclosed |