Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299580 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL27448738 | 0.84 | KCNQ2 (0.54) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL19388858 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL513878 | 0.82 | MEN1 (0.58) | SMN1; SMN2HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL11798134 | 0.81 | NPC1 (0.58) | SMN1; SMN2HPGDKDM4EALDH1A1MAOB | |
| SCHEMBL7256712 | 0.81 | GAA (0.56) | SMN1; SMN2HPGDALOX15MEN1KMT2A | |
| SCHEMBL7255889 | 0.80 | HPGD (0.54) | SMN1; SMN2HPGDALOX15KMT2ACYP1A2 | |
| SCHEMBL11801237 | 0.80 | HPGD (0.59) | SMN1; SMN2HPGDALOX15MEN1KMT2A | |
| SCHEMBL11794832 | 0.80 | HPGD (0.59) | SMN1; SMN2HPGDALOX15MEN1KMT2A | |
| SCHEMBL7305243 | 0.79 | ANPEP (0.52) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635665-B2 | applying aerosols of isopropyl-N-(chlorophenyl) carbamate to a stored potatoes crop, and aerosol may be generated by any suitable means using thermal aerosol generators or cool aerosol generators ( use of air in the generation of the aerosol and, or the cooling of the aerosol) | KEIM JOHN RAYMOND | 2009-12-22 | — | — | US | claimed |
| US-5932609-A | Pharmaceutical composition for inhibiting the growth of cancers | THE PROCTER & GAMBLE COMPANY (US) | 1999-08-03 | — | — | US | claimed |
| US-4857345-A | Compositions for the treatment of fruit and vegetables by thermal fogging and processing method using said composition | XEDA INTERNATIONAL (FR) | 1989-08-15 | — | — | US | claimed |
| EP-0161989-B1 | COMPOSITIONS FOR THE TREATMENT OF FRUITS AND VEGETABLES BY THERMAL FOGGING AND TREATMENT PROCESS USING THESE COMPOSITIONS | XEDA INTERNATIONAL (FR) | 1988-08-10 | — | — | EP | claimed |
| US-20170355997-A1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-12-14 | — | — | US | disclosed |
| US-20170355997-A1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-12-14 | — | — | US | disclosed |
| US-9771592-B2 | Methods and compositions for treating or preventing pruritis | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| US-9771592-B2 | Methods and compositions for treating or preventing pruritis | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| US-20140303231-A1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-10-09 | — | — | US | disclosed |
| WO-2012177971-A2 | POTATO BOX STORE CHEMICAL TREATMENTS | 1,4 GROUP, INC. (US) | 2012-12-27 | — | — | WO | disclosed |
| US-20120328767-A1 | POTATO BOX STORE CHEMICAL TREATMENTS | 1,4 GROUP, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120073001-A1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-03-22 | — | — | US | disclosed |
| CN-1165143-A | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-11-19 | — | — | CN | disclosed |
| CN-1165144-A | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-11-19 | — | — | CN | disclosed |
| US-4857345-A | Compositions for the treatment of fruit and vegetables by thermal fogging and processing method using said composition | XEDA INTERNATIONAL (FR) | 1989-08-15 | — | — | US | disclosed |
| EP-0161989-B1 | COMPOSITIONS FOR THE TREATMENT OF FRUITS AND VEGETABLES BY THERMAL FOGGING AND TREATMENT PROCESS USING THESE COMPOSITIONS | XEDA INTERNATIONAL (FR) | 1988-08-10 | — | — | EP | disclosed |
| EP-0161989-A1 | Compositions for the treatment of fruits and vegetables by thermal fogging and treatment process using these compositions | XEDA INTERNATIONAL (FR) | 1985-11-21 | — | — | EP | disclosed |
| EP-0032733-B1 | PROCESS FOR PREPARING POLYMETHYLENE POLYPHENYL POLYCARBAMATES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1984-06-13 | — | — | EP | disclosed |
| EP-0032733-A1 | Process for preparing polymethylene polyphenyl polycarbamates | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1981-07-29 | — | — | EP | disclosed |
| US-3938986-A | ISOPROPYL N-PHENYLCARBAMATE OR ISOPROPYL N-(3-CHLOROPHENYL)CARBAMATE AND 4-CHLOROPHENYL N-METHYLCARBAMATE | PPG INDUSTRIES, INC. (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355997-A1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS | ITCH, CCL11, CPA3 | SMN1; SMN2 3785/4885HPGD 503/4885ALOX15 158/4885 |
| US-20140303231-A1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS | ITCH, CCL11, CPA3 | SMN1; SMN2 3785/4885HPGD 503/4885ALOX15 158/4885 |
| US-20120073001-A1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS | ITCH, CCL11, CPA3 | SMN1; SMN2 3785/4885HPGD 503/4885ALOX15 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.