SCHEMBL7521138

SCHEMBL7521138

NCC(c1ccccn1)c1ccccc1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 6/20 0.43
SLC6A4 P31645 6/20 0.43
SLC6A3 Q01959 5/20 0.43
TSHR P16473 2/20 0.42
CHRM2 P08172 5/20 0.41
SCN1A P35498 3/20 0.41
SCN2A Q99250 3/20 0.41
SCN3A Q9NY46 3/20 0.41
CXCR4 P61073 1/20 0.39
ALDH1A1 P00352 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KCNH2 Q12809 5/20 0.37
KCNA5 P22460 1/20 0.37
HTR2A P28223 4/20 0.36
CYP1A2 P05177 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
PI4KA P42356 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3831711 0.85 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3TSHRCHRM2
SCHEMBL6933091 0.83 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3TSHRCHRM2
SCHEMBL7000006 0.79 ALDH1A1 (0.41) SLC6A2SLC6A4SLC6A3TSHRCHRM2
SCHEMBL6999607 0.79 ALDH1A1 (0.41) SLC6A2SLC6A4SLC6A3TSHRCHRM2
SCHEMBL1422822 0.78 SLC6A2 (0.59) SLC6A2SLC6A4SLC6A3TSHRCHRM2
SCHEMBL2066147 0.78 SLC6A2 (0.59) SLC6A2SLC6A4SLC6A3TSHRCHRM2
SCHEMBL27511961 0.78 SLC6A2 (0.59) SLC6A2SLC6A4SLC6A3TSHRCHRM2
Hydrochloric Acid SCHEMBL16702791 0.77 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3TSHRCHRM2
Hydrochloric Acid SCHEMBL7927468 0.77 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3TSHRCHRM2
Hydrochloric Acid SCHEMBL7864529 0.77 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3TSHRCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6365558-B2 POUR POINT DEPRESSANT AND POSSIBLY A PERFORMANCE ADDITIVE; ENVIRONMENTALLY FRIENDLY BASE FLUIDS IN INDUSTRIAL APPLICATIONS THE LUBRIZOL CORPORATION 2002-04-02 US disclosed
EP-0604125-B1 Pour point depressants for high monounsaturated vegetable oils and for high monounsaturated vegetable oils/biodegradable base and fluid mixtures LUBRIZOL CORP (US) 2002-03-13 EP disclosed
US-20010056045-A1 VEGETABLE OILS CONTAINING STYRENE/BUTADIENE COPOLYMERS IN COMBINATION WITH ADDITIONAL COMMERCIAL POLYMERS THAT HAVE GOOD LOW TEMPERATURE AND HIGH TEMPERATURE VISCOMETRICS LUBRIZOL CORPORATION, THE 2001-12-27 US disclosed
EP-0554421-B1 THE USE OF FUNCTIONALS FLUIDS COMPRISING TRIGLYCERIDES AND VARIOUS ADDITIVES AS TRACTOR OILS LUBRIZOL CORP (US) 2001-12-05 EP disclosed
EP-0602981-B1 Environmentally friendly viscosity index improving compositions LUBRIZOL CORP (US) 2000-03-15 EP disclosed
EP-0747466-B1 Vegetable oils containing styrene/butadiene copolymers in combination with additional commercial polymers that have good low temperature and high temperature viscometrics LUBRIZOL CORP (US) 2000-02-09 EP disclosed
EP-0626442-B1 Pour point depressant treated fatty acid esters as biodegradable, combustion engine fuels LUBRIZOL CORP (US) 1999-07-14 EP disclosed
US-5858934-A TRIGLYCERIDE, PERFORMANCE ADDITIVE, ANTIOXIDANTS AND VISCOSITY MODIFIERS THE LUBRIZOL CORPORATION (US) 1999-01-12 US disclosed
EP-0806469-A2 An enhanced biodegradable vegetable oil grease The Lubrizol Corporation (US) 1997-11-12 EP disclosed
US-5681797-A HYDROGENATED POLYISOPRENE WITH ALKYL PHENOLS OR PHENOLIC ETHERS, MONO- OR DIGLYCERIDES, PHOSPHOROUS COMPOUNDS WITH NITROGEN, OXYGEN AND/OR SULFUR, AROMATIC AMINES, SMALL POLYACRYLIC ESTERS OR POLYOLEFINS AS PERFORMANENCE ADDITIVES THE LUBRIZOL CORPORATION (US) 1997-10-28 US disclosed
US-5399275-A Environmentally friendly viscosity index improving compositions THE LUBRIZOL CORPORATION (US) 1995-03-21 US disclosed
EP-0626442-A1 Pour point depressant treated fatty acid esters as biodegradable, combustion engine fuels THE LUBRIZOL CORPORATION (US) 1994-11-30 EP disclosed
US-5338471-A Pour point depressants for industrial lubricants containing mixtures of fatty acid esters and vegetable oils THE LUBRIZOL CORPORATION (US) 1994-08-16 US disclosed
EP-0604125-A1 Pour point depressants for high monounsaturated vegetable oils and for high monounsaturated vegetable oils/biodegradable base and fluid mixtures The Lubrizol Corporation (US) 1994-06-29 EP disclosed
EP-0602981-A1 Environmentally friendly viscosity index improving compositions The Lubrizol Corporation (US) 1994-06-22 EP disclosed
US-5298177-A Power transmission fluids, overbased compounds, metal passivator, diarylamine, amine salt of carboxy containing copolymer THE LUBRIZOL CORPORATION (US) 1994-03-29 US disclosed
EP-0565661-A1 A BIODEGRADABLE CHAIN BAR LUBRICANT THE LUBRIZOL CORPORATION (US) 1993-10-20 EP disclosed
EP-0554421-A1 FUNCTIONAL FLUID WITH TRIGLYCERIDES, DETERGENT-INHIBITOR ADDITIVES AND VISCOSITY MODIFYING ADDITIVES THE LUBRIZOL CORPORATION (US) 1993-08-11 EP disclosed
WO-1993009209-A1 A BIODEGRADABLE CHAIN BAR LUBRICANT THE LUBRIZOL CORPORATION (US) 1993-05-13 WO disclosed
WO-1993003123-A1 FUNCTIONAL FLUID WITH TRIGLYCERIDES, DETERGENT-INHIBITOR ADDITIVES AND VISCOSITY MODIFYING ADDITIVES THE LUBRIZOL CORPORATION (US) 1993-02-18 WO disclosed