SCHEMBL7521246

SCHEMBL7521246

O=[N+]([O-])C=C(SCc1ccccc1)[S+]([O-])Cc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 8/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C19 P33261 2/20 0.35
POLB P06746 1/20 0.35
CYP2C9 P11712 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
LMNA P02545 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7992252 0.78 IDO1 (0.46) IDO1NOS3NOS1NOS2ALDH1A1
Potassium Ion SCHEMBL11782630 0.73 CA12 (0.42) IDO1NOS3NOS1NOS2ALDH1A1
SCHEMBL11782625 0.73 IDO1 (0.41) IDO1NOS3NOS1NOS2ALDH1A1
SCHEMBL11782623 0.73 IDO1 (0.41) IDO1NOS3NOS1NOS2ALDH1A1
SCHEMBL3262714 0.70 IDO1 (0.44) IDO1NOS3NOS1NOS2MEN1
SCHEMBL3263798 0.68 IDO1 (0.42) IDO1NOS3NOS1NOS2CYP1A2
SCHEMBL11466850 0.66 ALDH1A1 (0.46) IDO1NOS3NOS1NOS2ALDH1A1
SCHEMBL11466851 0.66 ALDH1A1 (0.46) IDO1NOS3NOS1NOS2ALDH1A1
SCHEMBL11362612 0.65 CES2 (0.47) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL11362610 0.65 CES2 (0.47) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765870-B1 Broad-spectrum antimicrobially active compounds ROHM & HAAS (US) 2002-02-13 EP claimed
CN-1160481-A Broad-spectrum antimicrobially active compounds ROHM & HAAS (US) 1997-10-01 CN claimed
EP-0765870-A2 Broad-spectrum antimicrobially active compounds ROHM AND HAAS COMPANY (US) 1997-04-02 EP claimed
EP-0765870-B1 Broad-spectrum antimicrobially active compounds ROHM & HAAS (US) 2002-02-13 EP disclosed
US-5883134-A APPLYING 1-(ALKYLSULFINYL- OR ALKYLSULFONYL)-2-NITROETHENE DERIVATIVE AS BACTERICIDE, FUNGICIDE, AND/OR ALGICIDE ROHM AND HAAS COMPANY (US) 1999-03-16 US disclosed
CN-1160481-A Broad-spectrum antimicrobially active compounds ROHM & HAAS (US) 1997-10-01 CN disclosed
EP-0765870-A2 Broad-spectrum antimicrobially active compounds ROHM AND HAAS COMPANY (US) 1997-04-02 EP disclosed