Sugi Predict

Sugi Predict / Compounds / SCHEMBL7521311

SCHEMBL7521311

SCHEMBL7521311

CNC(=O)/C(=N\OC)c1ccccc1COc1ncc(C(=O)c2ccccc2)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 8/20 0.45
▸ SCN9A Q15858 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ TP53 P04637 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ MRGPRX4 Q96LA9 2/20 0.35
▸ GCK P35557 1/20 0.34
▸ DHODH Q02127 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ NPC1 O15118 1/20 0.33
▸ NR4A2 P43354 1/20 0.33
▸ RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7521316 1.00 HIF1A (0.45) HIF1ASCN9AL3MBTL1TP53HTT
SCHEMBL8343050 0.93 HIF1A (0.46) HIF1ASCN9ATP53HTTMRGPRX4
SCHEMBL8343054 0.93 HIF1A (0.46) HIF1ASCN9ATP53HTTMRGPRX4
SCHEMBL7523038 0.91 HIF1A (0.44) HIF1ASCN9AL3MBTL1TP53HTT
SCHEMBL7523042 0.91 HIF1A (0.44) HIF1ASCN9AL3MBTL1TP53HTT
SCHEMBL8337626 0.91 HIF1A (0.45) HIF1ASCN9ATP53HTTMRGPRX4
SCHEMBL8337628 0.91 HIF1A (0.45) HIF1ASCN9ATP53HTTMRGPRX4
SCHEMBL16705532 0.88 HIF1A (0.48) HIF1ASCN9AL3MBTL1ALDH1A1
SCHEMBL829036 0.88 HIF1A (0.49) HIF1ASCN9ATP53HTTMRGPRX4
SCHEMBL829037 0.88 HIF1A (0.49) HIF1ASCN9ATP53HTTMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6436963-B1 FUNGICIDES DOW AGROSCIENCES LLC 2002-08-20 — — US disclosed
US-6432951-B1 FUNGICIDES DOW AGROSCIENCES LLC 2002-08-13 — — US disclosed
US-20020035259-A1 2-methoxyimino-2-(pyridinyloxymethyl)phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring CANADA EMILY J (US) 2002-03-21 — — US disclosed
US-20020035257-A1 2-methoxyimino-2-(pyridinyloxymethyl) phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring CANADA EMILY J (US) 2002-03-21 — — US disclosed
US-6306839-B1 FUNGICIDAL COMPOUNDS, AND THEIR USE IN FUNGICIDAL COMPOSITIONS COMPRISING AT LEAST ONE OF THE 2-METHOXYIMINO-2-(PYRIDINYLOXYMETHYL)PHENYL ACETAMIDE DOW AGROSCIENCES LLC 2001-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035259-A1 2-methoxyimino-2-(pyridinyloxymethyl)phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring AADAC, CYP1A2, NAAA HIF1A 4113/4885SCN9A 2122/4885L3MBTL1 4361/4885
US-20020035257-A1 2-methoxyimino-2-(pyridinyloxymethyl) phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring AADAC, CYP1A2, NAAA HIF1A 4113/4885SCN9A 2122/4885L3MBTL1 4361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.