Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942245 | 0.75 | KDM4E (0.53) | LMNAMAPTHTTIL2KDM4E | |
| SCHEMBL4447566 | 0.74 | KDM4E (0.51) | LMNAMAPTHTTIL2KDM4E | |
| SCHEMBL9087397 | 0.74 | HTT (0.43) | LMNAMAPTHTTIL2KDM4E | |
| SCHEMBL9088744 | 0.74 | HTT (0.43) | LMNAMAPTHTTIL2KDM4E | |
| SCHEMBL371 | 0.74 | KDM4E (0.49) | LMNAMAPTHTTIL2KDM4E | |
| SCHEMBL8630585 | 0.72 | KDM4E (0.47) | LMNAMAPTHTTIL2KDM4E | |
| SCHEMBL10742028 | 0.72 | ATM (0.47) | LMNAMAPTHTTIL2KDM4E | |
| SCHEMBL8560175 | 0.71 | HTT (0.41) | LMNAMAPTHTTIL2KDM4E | |
| SCHEMBL20411007 | 0.71 | HRH3 (0.54) | LMNAMAPTHTTIL2KDM4E | |
| SCHEMBL9087599 | 0.70 | HTT (0.40) | LMNAMAPTHTTIL2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122234-A9 | Production methods of alpha, alpha, alpha-trifluoromethylphenyl-substituted benzoic acid and intermediate therefor | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2002-01-16 | — | — | EP | disclosed |
| EP-1122234-A2 | Production methods of alpha, alpha, alpha-trifluoromethylphenyl-substituted benzoic acid and intermediate therefor | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |