Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | IL2 | P60568 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089149 | 0.86 | HTT (0.42) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL8624720 | 0.83 | HTT (0.42) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL9088744 | 0.81 | HTT (0.43) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL9087599 | 0.81 | HTT (0.40) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL8622918 | 0.80 | HTT (0.47) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL23748160 | 0.76 | MAPT (0.39) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL23748196 | 0.74 | MAPT (0.42) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL7521692 | 0.74 | LMNA (0.45) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL9089557 | 0.73 | KDM4E (0.42) | HTTLMNAMAPTKDM4EIL2 | |
| SCHEMBL9330422 | 0.73 | ATM (0.48) | HTTLMNAMAPTKDM4EIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585491-A | Antibacterial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0398967-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4920120-A | 3-CARBOXY, 4-OXO, 6-FLUORO, 7-NITROGEN-CONTAINING RING 1,4-DIHYDRO-1,8-NAPHTHYRIDINES | WARNER-LAMBERT COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0326891-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| WO-1989006649-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-07-27 | — | — | WO | disclosed |