Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878833 | 0.87 | CYP19A1 (0.32) | CYP19A1LMNAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL29240039 | 0.85 | CYP19A1 (0.33) | CYP19A1LMNAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27503789 | 0.81 | CYP19A1 (0.32) | ALDH1A1CYP19A1LMNA | |
| SCHEMBL28413104 | 0.79 | PRKCA (0.39) | CYP19A1LMNAMAPTNR3C1PGR | |
| SCHEMBL4564982 | 0.78 | CYP19A1 (0.39) | CYP19A1 | |
| SCHEMBL28457918 | 0.75 | BCL9 (0.35) | ALDH1A1CYP19A1 | |
| SCHEMBL14478385 | 0.73 | CYP19A1 (0.46) | ALDH1A1CYP19A1LMNA | |
| SCHEMBL28870848 | 0.72 | CYP19A1 (0.35) | CYP19A1MAPT | |
| SCHEMBL14478384 | 0.72 | CYP19A1 (0.49) | ALDH1A1CYP19A1LMNA | |
| SCHEMBL30992129 | 0.71 | POLB (0.34) | ALDH1A1CYP19A1LMNAGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060986-A9 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN INC (US) | 2002-10-17 | — | — | WO | claimed |
| WO-2001060986-A2 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN, INC. (US) | 2001-08-23 | — | — | WO | claimed |
| WO-2001060986-A9 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN INC (US) | 2002-10-17 | — | — | WO | disclosed |
| WO-2001060986-A2 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN, INC. (US) | 2001-08-23 | — | — | WO | disclosed |