Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519830 | 0.86 | ADORA1 (0.43) | NT5EABCB1KMT2ASYK | |
| SCHEMBL7529881 | 0.82 | NT5E (0.39) | NT5ECXCR2L3MBTL1ABCB1PDE4D | |
| SCHEMBL7519817 | 0.81 | ADORA1 (0.42) | ABCB1KMT2ASYK | |
| SCHEMBL5770835 | 0.74 | NT5E (0.41) | NT5ECXCR2KMT2A | |
| SCHEMBL7211425 | 0.74 | L3MBTL1 (0.39) | NT5EL3MBTL1KMT2ANPSR1 | |
| SCHEMBL5837674 | 0.73 | PTPN2 (0.37) | NT5ECXCR2L3MBTL1 | |
| SCHEMBL5838518 | 0.72 | CXCR2 (0.36) | NT5ECXCR2L3MBTL1KMT2A | |
| SCHEMBL5769823 | 0.69 | PTPN1 (0.46) | CXCR2 | |
| SCHEMBL7520724 | 0.69 | ADORA1 (0.45) | ABCB1KMT2ASYK | |
| SCHEMBL5838317 | 0.69 | CXCR2 (0.33) | NT5ECXCR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPN1, PTPRO, PTPRS | NT5E 825/4885CXCR2 739/4885L3MBTL1 3145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.