SCHEMBL7521840

SCHEMBL7521840

COc1cc(C)c(C(=O)c2c(OC)ccc3ccccc23)c(OC)c1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 5/20 0.57
CNR2 P34972 3/20 0.50
CNR1 P21554 1/20 0.50
ABCG2 Q9UNQ0 3/20 0.46
MAPT P10636 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43
HTT P42858 1/20 0.43
BLM P54132 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP1A1 P04798 1/20 0.42
NCEH1 Q6PIU2 1/20 0.41
ABCB1 P08183 1/20 0.41
TUBB4A P04350 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7601885 0.92 CTSD (0.51) CTSDCNR2CNR1ABCG2MAPT
SCHEMBL7520103 0.90 CTSD (0.50) CTSDCNR2CNR1ABCG2MAPT
SCHEMBL23499947 0.84 CNR2 (0.59) CTSDCNR2CNR1ABCG2MAPT
SCHEMBL27813524 0.81 ACHE (0.45) MAPTMEN1KMT2AKDM4EHPGD
SCHEMBL6740389 0.79 KCNB1 (0.47) ABCG2KMT2ASMN1; SMN2ABCB1TUBB4A
SCHEMBL7943881 0.79 ATM (0.54) MAPTMEN1KMT2AKDM4EHPGD
SCHEMBL7519964 0.79 KRAS (0.47) ABCG2MAPTMEN1KMT2AKDM4E
SCHEMBL29625745 0.77 ABCG2 (0.57) CTSDCNR2CNR1ABCG2MAPT
SCHEMBL24954211 0.77 ABCG2 (0.57) CTSDCNR2CNR1ABCG2MAPT
SCHEMBL7601071 0.77 CTSD (0.45) CTSDMAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0897904-B1 Fungicidal 2-methoxybenzophenones BASF AG (DE) 2002-02-20 EP claimed
US-5945567-A Fungicidal 2-methoxybenzophenones AMERICAN CYANAMID COMPANY (US) 1999-08-31 US claimed
EP-0897904-A1 Fungicidal 2-methoxybenzophenones American Cyanamid Company (US) 1999-02-24 EP claimed
CN-1300084-C 2-methoxy diphenyl ketone compound intermediate and its preparation method AMERICAN CYANAMID CO (US) 2007-02-14 CN disclosed
CN-1495153-A 2-methoxy diphenyl ketone compound intermediate and its preparation method 2004-05-12 CN disclosed
CN-1147456-C Fungicidal 2-methoxybenzophenones 2004-04-28 CN disclosed
EP-0897904-B1 Fungicidal 2-methoxybenzophenones BASF AG (DE) 2002-02-20 EP disclosed
US-6001883-A SUBSTITUTED BENZOPHENONES OF GIVEN FORMULA, SUCH AS 6,6'-DIMETHYL-2,2',3',4'-TETRAMETHOXY-5-TRIFLUOROMETHYL-BENZOPHENONE; HIGHLY SYSTEMIC FUNGICIDES; CONTROLLING FUNGAL DISEASE SUCH AS POWDERY MILDEW IN PLANTS AMERICAN CYANAMID COMPANY (US) 1999-12-14 US disclosed
US-5945567-A Fungicidal 2-methoxybenzophenones AMERICAN CYANAMID COMPANY (US) 1999-08-31 US disclosed
US-5922905-A INTERMEDIATES FOR FUNGICIDES AMERICAN CYANAMID COMPANY (US) 1999-07-13 US disclosed
EP-0897904-A1 Fungicidal 2-methoxybenzophenones American Cyanamid Company (US) 1999-02-24 EP disclosed