Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727156 | 0.86 | CTSK (0.52) | CTSKCTSSCYP2D6CA2CA1 | |
| SCHEMBL24469490 | 0.80 | CTSK (0.51) | CTSKCTSSCYP2D6CA2CA1 | |
| SCHEMBL7893209 | 0.79 | CTSK (0.49) | CTSKCTSSCYP2D6CA2CA1 | |
| SCHEMBL7888254 | 0.79 | CTSK (0.49) | CTSKCTSSCYP2D6CA2CA1 | |
| SCHEMBL3727425 | 0.79 | CTSK (0.49) | CTSKCTSSCYP2D6CA2CA1 | |
| SCHEMBL23260554 | 0.79 | CTSK (0.57) | CTSKCTSSCYP2D6CA2CA1 | |
| SCHEMBL16658566 | 0.78 | CTSK (0.54) | CTSKCTSSCYP2D6CA2CA1 | |
| SCHEMBL3180779 | 0.78 | CTSK (0.54) | CTSKCTSSCYP2D6CA2CA1 | |
| SCHEMBL17011363 | 0.78 | CTSK (0.54) | CTSKCTSSCYP2D6CA2CA1 | |
| SCHEMBL1515310 | 0.78 | CTSK (0.54) | CTSKCTSSCYP2D6CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128301-A1 | Non-nucleoside reverse transcriptase inhibitors | AB, Medivir (SE) | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128301-A1 | Non-nucleoside reverse transcriptase inhibitors | SUB1, CBR1, GAR1 | CTSK 3753/4885CTSS 2072/4885CYP2D6 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.