Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 3/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | CPT1A | P50416 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203743 | 0.81 | CYP3A4 (0.51) | CYP3A4 | |
| SCHEMBL752801 | 0.78 | CYP3A4 (0.40) | CYP3A4CPT1A | |
| SCHEMBL18534458 | 0.76 | CYP3A4 (0.41) | CYP3A4CPT1A | |
| SCHEMBL750891 | 0.75 | CYP3A4 (0.38) | CYP3A4CPT1A | |
| SCHEMBL16986624 | 0.75 | CYP3A4 (0.38) | CYP3A4CPT1A | |
| SCHEMBL17656270 | 0.74 | CYP3A4 (0.49) | CYP3A4 | |
| SCHEMBL18534351 | 0.72 | KMT2A (0.38) | — | |
| SCHEMBL748770 | 0.72 | CYP3A4 (0.59) | CYP3A4 | |
| SCHEMBL15349797 | 0.71 | CYP3A4 (0.45) | CYP3A4 | |
| SCHEMBL18534469 | 0.71 | HCRTR1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596936-B | Antiviral compounds | GILEAD SCIENCES INC | 2014-06-11 | — | — | CN | disclosed |
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |