Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413111 | 0.87 | GAA (0.56) | LMNACFDKDM4EGAAPTGS2 | |
| SCHEMBL3220624 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNATSHRADRA2ACYP2D6 | |
| SCHEMBL7411870 | 0.85 | LMNA (0.43) | SMN1; SMN2LMNATSHRCYP2C9CFD | |
| SCHEMBL6628635 | 0.81 | HTT (0.52) | SMN1; SMN2LMNATSHRADRA2ACYP2D6 | |
| SCHEMBL2825071 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNATSHRADRA2ACYP2D6 | |
| SCHEMBL21184279 | 0.80 | LMNA (0.46) | SMN1; SMN2LMNATSHRADRA2ACYP2D6 | |
| SCHEMBL6628554 | 0.78 | S1PR3 (0.49) | SMN1; SMN2LMNATSHRADRA2ACYP2D6 | |
| SCHEMBL6629256 | 0.78 | LMNA (0.47) | SMN1; SMN2LMNATSHRADRA2ACYP2D6 | |
| SCHEMBL2642603 | 0.78 | CA2 (0.61) | LMNATSHRKDM4EALDH1A1GAA | |
| SCHEMBL2642601 | 0.78 | LMNA (0.47) | SMN1; SMN2LMNATSHRADRA2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935511-A | Nervous system, gastrointestinal disorders | RORER PHARMACEUTICAL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |