Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | GPR3 | P46089 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10518195 | 0.82 | MAOA (0.64) | ERN1MAOAMAOBGPR3ALDH1A1 | |
| SCHEMBL25049845 | 0.80 | ERN1 (0.61) | ERN1GPR3ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL2125436 | 0.80 | MAOA (0.61) | ERN1MAOAMAOBGPR3ALDH1A1 | |
| SCHEMBL10157171 | 0.78 | MAOA (0.59) | ERN1MAOAMAOBGPR3ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27928855 | 0.78 | MAOA (0.59) | ERN1MAOAMAOBGPR3ALDH1A1 | |
| SCHEMBL11877337 | 0.78 | PKM (0.55) | ALDH1A1CYP1A2RAD52KDM4EMAPT | |
| SCHEMBL12877168 | 0.77 | MAOA (0.57) | ERN1MAOAMAOBGPR3ALDH1A1 | |
| SCHEMBL13191573 | 0.77 | MAOA (0.57) | ERN1MAOAMAOBGPR3ALDH1A1 | |
| SCHEMBL3892400 | 0.77 | ERN1 (0.57) | ERN1GPR3ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL6784629 | 0.77 | ERN1 (0.57) | ERN1GPR3ALDH1A1CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827986-B1 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-5955614-A | Bridged perinones/quinophthalones | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| EP-0827986-A2 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 1998-03-11 | — | — | EP | disclosed |