Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 14/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521871 | 0.94 | SUV39H2 (0.51) | SUV39H2DRD2DRD3CKS1BSKP1 | |
| SCHEMBL25703973 | 0.86 | SUV39H2 (0.54) | SUV39H2KDM4D | |
| SCHEMBL25285177 | 0.86 | SUV39H2 (0.54) | SUV39H2KDM4D | |
| SCHEMBL25453975 | 0.86 | SUV39H2 (0.55) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL12841264 | 0.83 | SUV39H2 (0.52) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL30424379 | 0.83 | SUV39H2 (0.64) | SUV39H2 | |
| SCHEMBL1800785 | 0.82 | SUV39H2 (0.54) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL4580200 | 0.82 | CTSK (0.50) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL4580205 | 0.82 | CTSK (0.50) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL27655935 | 0.82 | SUV39H2 (0.54) | SUV39H2DRD2DRD3CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171432-A1 | ADAMANTANE DERIVATIVES | AstraZeneca AB (SE) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000061569-A1 | ADAMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |