Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524572 | 0.93 | FTO (0.33) | KDM4EMMP12HTTATMFTO | |
| SCHEMBL7525432 | 0.85 | KDM4E (0.34) | KDM4EMMP12HTTATMFTO | |
| SCHEMBL10100884 | 0.80 | — | — | |
| SCHEMBL9291596 | 0.80 | MAPT (0.41) | KDM4EHTTFTOALDH1A1MAPT | |
| SCHEMBL12352021 | 0.78 | DRD1 (0.35) | — | |
| SCHEMBL7525551 | 0.77 | FTO (0.54) | KDM4EHTTATMFTOAKR1B1 | |
| SCHEMBL7523777 | 0.77 | FTO (0.38) | FTO | |
| SCHEMBL7520930 | 0.76 | FTO (0.52) | KDM4EATMFTOAKR1B1SLC6A2 | |
| SCHEMBL13668278 | 0.75 | KDM4E (0.43) | KDM4EAKR1B1MAPTRXRA | |
| SCHEMBL13668353 | 0.75 | RXRA (0.53) | CYP26A1CYP26B1ALDH1A1RXRATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738723-B1 | Method for making polyalkylated xanthenes | GEN ELECTRIC (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-0738723-A2 | Method for making polyalkylated xanthenes | GENERAL ELECTRIC COMPANY (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5554770-A | Method for making polyalkylated xanthenes | GENERAL ELECTRIC COMPANY (US) | 1996-09-10 | — | — | US | disclosed |