Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 7/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 6/20 | 0.37 |
| ▸ | HTR1D | P28221 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517920 | 0.83 | MAPT (0.50) | HTR1BMAPTNR5A1TP53TSHR | |
| SCHEMBL7525065 | 0.83 | MAPT (0.47) | HTR1BMAPTHTR1AHTR1DMAPK1 | |
| SCHEMBL7519044 | 0.83 | NR5A1 (0.51) | HTR1BMTNR1AMAPTNR5A1MEN1 | |
| SCHEMBL7528065 | 0.82 | MAPK1 (0.41) | HTR1BMTNR1AMAPTHTR1AHTR1D | |
| SCHEMBL8767604 | 0.80 | NR5A1 (0.34) | HTR1BMAPTHTR1AHTR1DMAPK1 | |
| SCHEMBL7520990 | 0.79 | S1PR1 (0.38) | HTR1BMAPTPDE2AALDH2 | |
| SCHEMBL8720511 | 0.76 | MAPT (0.43) | MTNR1AMAPTNR5A1KDM4ETP53 | |
| SCHEMBL7515612 | 0.74 | CYP3A4 (0.41) | MAPTMAPK1NR5A1CYP3A4CYP2D6 | |
| SCHEMBL12485019 | 0.73 | NR5A1 (0.58) | HTR1BMAPTHTR1AHTR1DMAPK1 | |
| SCHEMBL12483695 | 0.73 | NR5A1 (0.58) | HTR1BMAPTHTR1AHTR1DMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946513-B1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2002-01-30 | — | — | EP | disclosed |
| US-6120703-A | Derivatives of 6-fluorophenanthridine for liquid crystal mixtures | AVENTIS RESEARCH & TECHNOLOGIES DEUTSCHLAND GMBH & CO. KG (DE) | 2000-09-19 | — | — | US | disclosed |
| EP-0946513-A1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | Aventis Research & Technologies GmbH & Co. KG (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027060-A1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-06-25 | — | — | WO | disclosed |