Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 8/20 | 0.40 |
| ▸ | HTR1A | P08908 | 7/20 | 0.40 |
| ▸ | HTR1D | P28221 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515612 | 0.89 | CYP3A4 (0.41) | MAPK1CYP3A4MEN1KMT2AUSP2 | |
| SCHEMBL7519021 | 0.86 | S1PR1 (0.37) | MAPK1CYP3A4MEN1KMT2AUSP2 | |
| SCHEMBL7519026 | 0.86 | S1PR1 (0.37) | MAPK1CYP3A4MEN1KMT2AUSP2 | |
| SCHEMBL7519018 | 0.86 | S1PR1 (0.37) | MAPK1CYP3A4MEN1KMT2AUSP2 | |
| SCHEMBL7519044 | 0.84 | NR5A1 (0.51) | MEN1KMT2AALDH1A1HTR1BMAPT | |
| SCHEMBL7525065 | 0.84 | MAPT (0.47) | MAPK1CYP3A4MEN1KMT2AHTR1B | |
| SCHEMBL7522690 | 0.82 | HTR1B (0.38) | MAPK1CYP3A4MEN1KMT2AHTR1B | |
| SCHEMBL7517920 | 0.82 | MAPT (0.50) | LMNAHTR1BMAPTTP53 | |
| SCHEMBL7517995 | 0.81 | CYP3A4 (0.49) | CYP3A4MEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL7523369 | 0.79 | EIF4A1 (0.41) | CYP3A4ALDH1A1LMNASMN1; SMN2HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946513-B1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2002-01-30 | — | — | EP | disclosed |
| US-6120703-A | Derivatives of 6-fluorophenanthridine for liquid crystal mixtures | AVENTIS RESEARCH & TECHNOLOGIES DEUTSCHLAND GMBH & CO. KG (DE) | 2000-09-19 | — | — | US | disclosed |
| EP-0946513-A1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | Aventis Research & Technologies GmbH & Co. KG (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027060-A1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-06-25 | — | — | WO | disclosed |