Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525065 | 0.85 | MAPT (0.47) | NR5A1MEN1MAPTKMT2AGPBAR1 | |
| SCHEMBL7528065 | 0.84 | MAPK1 (0.41) | MEN1ALDH1A1MAPTKMT2ACNR2 | |
| SCHEMBL7522690 | 0.83 | HTR1B (0.38) | NR5A1ALDH2MEN1MAPTKMT2A | |
| SCHEMBL7517920 | 0.83 | MAPT (0.50) | NR5A1MAPTGPBAR1CYSLTR2CYSLTR1 | |
| SCHEMBL7524265 | 0.80 | CYP3A4 (0.49) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL7520990 | 0.78 | S1PR1 (0.38) | ALDH2MAPTHTR1B | |
| SCHEMBL7517995 | 0.78 | CYP3A4 (0.49) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL7515612 | 0.76 | CYP3A4 (0.41) | NR5A1MEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL9697418 | 0.75 | NR5A1 (0.71) | NR5A1LTA4HALDH2MEN1NPC1 | |
| SCHEMBL9001511 | 0.75 | NR5A1 (0.71) | NR5A1LTA4HALDH2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946513-B1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2002-01-30 | — | — | EP | disclosed |
| US-6120703-A | Derivatives of 6-fluorophenanthridine for liquid crystal mixtures | AVENTIS RESEARCH & TECHNOLOGIES DEUTSCHLAND GMBH & CO. KG (DE) | 2000-09-19 | — | — | US | disclosed |
| EP-0946513-A1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | Aventis Research & Technologies GmbH & Co. KG (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027060-A1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-06-25 | — | — | WO | disclosed |