Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.45 |
| ▸ | FEN1 | P39748 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510099 | 0.94 | GPR119 (0.50) | IDO1TDO2GPR119CHRNB2CHRNA4 | |
| SCHEMBL29960962 | 0.94 | GPR119 (0.50) | IDO1TDO2GPR119CHRNB2CHRNA4 | |
| SCHEMBL7524187 | 0.83 | GPR119 (0.49) | IDO1TDO2GPR119ALOX5APFEN1 | |
| SCHEMBL7513551 | 0.83 | GPR119 (0.49) | IDO1TDO2GPR119ALOX5APFEN1 | |
| SCHEMBL7525477 | 0.83 | GPR119 (0.49) | IDO1TDO2GPR119ALOX5APFEN1 | |
| SCHEMBL21398088 | 0.83 | GPR119 (0.53) | IDO1TDO2GPR119ALOX5APFEN1 | |
| SCHEMBL26311640 | 0.83 | GPR119 (0.53) | IDO1TDO2GPR119ALOX5APFEN1 | |
| SCHEMBL7463050 | 0.81 | PIK3CD (0.48) | IDO1TDO2GPR119CHEK2 | |
| SCHEMBL7465754 | 0.81 | PIK3CD (0.48) | IDO1TDO2GPR119CHEK2 | |
| SCHEMBL14778459 | 0.81 | PIK3CD (0.48) | IDO1TDO2GPR119CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151712-A1 | 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission | LIN NAN-HORNG (US) | 2002-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151712-A1 | 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission | GAP43, SLC18A2, GABRE | IDO1 4137/4885TDO2 2266/4885GPR119 604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.