SCHEMBL7522947

SCHEMBL7522947

CC(=O)NCCCc1cccc2c1OCCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 19/20 1.00
MTNR1B P49286 7/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7523147 0.96 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL1010497 0.92 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7520573 0.85 MTNR1A (0.73) MTNR1AMTNR1B
SCHEMBL7522254 0.83 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL6948606 0.83 MTNR1A (0.70) MTNR1AMTNR1B
SCHEMBL1011204 0.82 MTNR1A (0.82) MTNR1AMTNR1B
SCHEMBL7526194 0.81 MTNR1A (0.68) MTNR1AMTNR1B
SCHEMBL7530999 0.81 MTNR1A (0.68) MTNR1AMTNR1B
SCHEMBL8481998 0.80 MTNR1A (0.67) MTNR1AMTNR1B
SCHEMBL7526974 0.80 MTNR1A (1.00) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0873993-B1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2002-02-20 EP disclosed
US-5919814-A Heterocyclic compounds ADIR ET COMPAGNIE (FR) 1999-07-06 US disclosed
EP-0873993-A1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1998-10-28 EP disclosed